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Associate Scientist ~ Scientist I

◔ Full-Time
➣ Location: Suzhou, PRC
☉ Junior-Mid Level

Job Description

Responsibility:

  • The main scope of work involves the antibody drug conjugate (ADC) research and development;
  • Conduct experiments to explore the scope and limitations for process development and optimization of ADC conjugation. Participate in analytical characterization for ADCs, such as DAR, residual free drug, aggregation level, endotoxin, etc. Skilled in literature searching about ADC.
  • Assist ADC experiment design, project management and cross-functional collaboration to ensure ADC project progress as planned;
  • Identify and solve problems in the experiment, rationally explain the observed experimental results, and timely adjust the project plan according to the progress;
  • Maintain a compliant experimental record, including conclusions, plan for next step, and thorough characterization of the product;
  • Support the daily work of the project leader and report the progress to the supervisor regularly.

Requirements:

  • Bachelor degree or above in biology, chemistry, bioengineering or related field, working experience in Biotech, Biopharma, CRO or CDMO is preferred;
  • More than 3 years work experience in ADC conjugation with a Bachelor degree and more than 1 year with a Master degree;
  • Have a certain understanding of ADC drugs, or relevant work experience is preferred;
  • Familiar with various conjugation techniques is preferred. Familiar with at least one conventional random conjugation(lysine or cysteine) or one site-specific conjugation (including but not limited to unnatural amino acid, engineered cysteine, N-glycan remodeling, K-lock, C-lock, affinity labeling, Sortase A ligation, mTGase ligation, etc.);
  • Good experimental skills and habits;
  • Proficient in the use of common laboratory equipment (such as HI-HPLC, RP-HPLC, SEC-HPLC, etc.) is preferred;
  • Keen interest in new drug research and development, willing to learn new things and knowledge;
  • Strong sense of responsibility, dedication, innovation, team spirit, and a sense of intellectual property confidentiality;
  • Good ability to summarize and report experiment results.

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