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Scientist I – Senior Scientist I, Therapeutic Antibody Discovery

◔ Full-Time
➣ Location: Suzhou, China
☉ Junior Level

Job Responsibility:

  • Design, perform, and optimize functional in vitro assays, including ELISA, flow-based
    reporter/blocking assays (FACS), and proliferation assays to evaluate antibody activity.
  • Establish and maintain primary cell cultures, and conduct primary cell-based functional assays to
    assess antibody mechanism of action.
  • Execute antibody screening and characterization workflows, from initial hit validation to lead
    selection, using both plate-based and cell-based readouts.
  • Analyze, interpret, and present experimental data with scientific rigor, drawing meaningful
    conclusions to guide project decision-making.
  • Maintain accurate and detailed experimental records, following company quality and
    documentation standards.
  • Contribute to the development of new assay platforms and process improvements to increase
    throughput and robustness.

Requirements:

  • Proven hands-on experience with ELISA, flow cytometry-based reporter/blocking assays,
  • proliferation assays, and other functional readouts.
  • Solid experience with primary cell culture (e.g., immune cells, tumor cells) and functional assay
    design.
  • Antibody screening experience, including hit triaging and functional ranking of candidates.
  • Proficiency in data analysis using statistical software (e.g., GraphPad Prism, FlowJo, Excel).
  • Ability to work independently and manage multiple projects in a fast-paced environment.
  • (Preferred) Experience in therapeutic antibody drug discovery, including mechanism-of-action
    studies.
  • (Preferred) Knowledge of cell signaling pathways relevant to immuno-oncology, inflammation, or
    other therapeutic areas.

If you are interested in joining our team, please send your resume to our HR department at nona.hr@nonabio.com.

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