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HCAb PLUS™

HCAb PLUS™ represents the cutting-edge evolution in therapeutic modalities, harnessing the power of fully human heavy chain-only antibodies (HCAbs).
Multi-Specific
ADC
CAR-Based
mRNA
  • The world’s first fully human HCAb platform
  • Clinically validated fully human HCAb
  • Experimentally proven applications of HCAb PLUS™
Bispecific/Multi-Specific

HCAb +
Antibody/
Protein

Explore HBICE

Nona Biosciences’ proprietary HBICE® (HCAb-Based Immune Cell Engager) facilitates the creation of innovative bispecifics, multispecifics, immunocytokines, and other modalities featuring simplified structures, reduced size, and fewer chains.

Bispecific Antibody
Bispecific
“Mini-Body”
Immunocytokine
HCAb PLUS™ ADC

HCAb + Payload

Explore Our ADC Project

Nona Biosciences’ featured HCAbs showcase superior applications in ADC, RDC, PROTAC, and related directions owing to their small size, low immunogenicity, high solubility, remarkable stability, excellent tissue penetration, conjugation advantages, and ease of production.

HCAb-ADC
HCAb-RDC
HCAb-PROTAC
HCAb PLUS™ CAR

HCAb + Cell

Explore Our CAR-T Project

Fully human HCAbs from Nona’s HCAb Harbour Mice® represent the ideal modalities for CAR-based cell therapies, potentially reducing immunogenicity. Their compact size, simplified structure, and precisely calibrated binding offer versatility in CAR design. Furthermore, NonaCarFx offers innovative direct CAR-function-based HCAb library screening platform enhances the discovery of powerful HCAbs.

Bispecific CAR-T Cell
CAR-NK
Cell
CAR-M
Cell
HCAb PLUS™ LNPs

HCAb + Nanoparticle

Explore Our LNPs Project

Nona Biosciences unveils the full potential of fully human HCAbs in mRNA therapies and targeted deliveries. Their small size and simplified structure enable superior mRNA designs and LNP modifications.

mRNA-LNP Expressing Bispecific Antibody
Targeted Drug Delivery

Start your Harbour Mice HCAb PLUS™ Project

Having questions? Contact us at BD@nonabio.com

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Ready to pioneer the next wave of biotech innovation? Contact us today and let’s embark on a journey to transform your ideas into reality.

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